[1]于军强,李力翠,王晓茹,等.含龙胆草提取物的液体敷料联合依巴斯汀治疗面部敏感性皮肤的疗效及其对皮肤生理功能的影响[J].中国美容医学,2024,(5):79-82.
　YU Junqiang,LI Licui,WANG Xiaoru,et al.Effi cacy of Liquid Dressing Containing Gentian Extract Combined with Ebastine on Facial Sensitive Skin and Its Infl uence on Skin Physiological Function[J].Medical Aesthetics and Beauty,2024,(5):79-82.
点击复制

含龙胆草提取物的液体敷料联合依巴斯汀治疗面部敏感性皮肤的疗效及其对皮肤生理功能的影响()
分享到：

《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:
期数:
2024年5期
页码:
79-82
栏目:
出版日期:
2024-05-10

文章信息/Info

Title:
Effi cacy of Liquid Dressing Containing Gentian Extract Combined with Ebastine on Facial Sensitive Skin and Its Infl uence on Skin Physiological Function
文章编号:
1008-6455（2024）05-0079-03
作者:
于军强1 ; 李力翠2 ; 王晓茹3 ; 毛 伟3 ; 杨祎峰4
(藁城市人民医院 1. 药剂科;2.皮肤科;3.医务科;4.中医科 河北 石家庄 052160 )
Author(s):
YU Junqiang1 ;  LI Licui2 ;  WANG Xiaoru3 ;  MAO Wei3 ;  YANG Weifeng4
( 1.Department of Pharmacy, 2.Department of Dermatology, 3.Department of Medical Management, 4.Department of Traditional Chinese Medicine, the People’s Hospital of Gaocheng, Shijiazhuang 052160, Hebei, China )
关键词:
面部; 敏感性皮肤; 龙胆草提取物; 液体敷料; 依巴斯汀; 皮肤生理功能
Keywords:
facial;  sensitive skin;  gentian extract;  liquid dressing;  ebastine;  skin physiological function
分类号:
R758.1
文献标志码:
A
摘要:
目的：探讨含龙胆草提取物的液体敷料联合依巴斯汀治疗面部敏感性皮肤的疗效及其对皮肤生理功能的影响。方法： 按照随机数字表法将2021年10月-2022年12月笔者医院收治的90例面部敏感性皮肤患者分为对照组与观察组，每组45例。对 照组使用依巴斯汀治疗，观察组使用含龙胆草提取物的液体敷料联合依巴斯汀治疗，均连续治疗4周。比较两组的疗效，乳 酸刺激试验指标，皮肤生理功能指标[经皮水分丢失量（Transepidermal water loss ，TEWL）、皮脂含量、角质层含水量、 皮肤pH值]及不良反应。结果：治疗结束后，观察组的总有效率（93.33% vs 71.11%）明显高于对照组（P＜0.05）；两组乳 酸刺激试验指标，皮肤生理功能指标均治疗前明显改善（P＜0.05）；观察组乳酸刺痛评分明显低于对照组（P＜0.05），乳 酸刺痛感开始时间明显长于对照组（P＜0.05）；观察组TEWL、皮肤pH值明显低于对照组（P＜0.05），皮脂含量、角质层含 水量明显高于对照组（P＜0.05）。两组均无严重不良反应发生。结论：含龙胆草提取物的液体敷料联合依巴斯汀能明显提 高面部敏感性皮肤的临床疗效，明显改善皮肤生理功能及耐受性，安全性好。
Abstract:
Objective To discuss the effi cacy of liquid dressing containing Gentian extract combined with ebastine on facial sensitive skin and its influence on skin physiological function. Methods According to random number table method, 90 patients with facial sensitive skin who were divided into control group and observation group in the author’s hospital from October 2021 to December 2022, with 45 cases in each group. The patients were treated with ebastine in control group, and the patients were treated with liquid dressing containing gentian extract combined with ebastine in observation group, all the patients were continuously treated for 4 weeks. The effi cacy, lactic acid stimulation test indexes, skin physiological function indexes[Transepidermal water loss(TEWL), sebum content, cuticle water content, skin pH value] and adverse reactions were compared between two groups. Results After treatment, the total eff ective rates(93.33% vs 71.11%) in observation group were signifi cantly higher than that in control group (P ＜0.05). The lactic acid stimulation test indexes and skin physiological function indexes were signifi cantly improved before treatment in both groups (P ＜0.05) .The lactic acid sting score in observation group were signifi cantly lower than that in control group(P ＜0.05), the onset time of lactic acid tingling sensation [(6.97±0.84)min vs (5.19±0.63)min] in observation group were signifi cantly longer than that in control group (P ＜0.05). The TEWL in observation group were signifi cantly lower than that in control group (P ＜0.05), the sebum content, cuticle water content in observation group were signifi cantly higher than that in control group (P ＜0.05). There were no serious adverse reactions in the two groups. Conclusion The liquid dressing containing gentian extract combined with ebastine could signifi cantly improve the clinical effi cacy, skin physiological function and tolerance of facial sensitive skin, and the safety was good.

相似文献/References:

[1]倪晓静,王 坤. “风筝”皮瓣修复面部皮肤缺损的临床应用[J].中国美容医学,2018,(04):27.
　NI Xiao-jing,WANG Kun. Clinical Application of Kite Flap to Repair Facial Skin Defect[J].Medical Aesthetics and Beauty,2018,(5):27.
[2]姚晓东,吴晓琰,崔晓美,等. 双极射频联合左旋维生素C治疗面部皮肤光老化疗效观察[J].中国美容医学,2018,(07):94.
　YAO Xiao-dong,WU Xiao-yan,CUI Xiao-mei,et al. The Clinical Survey of Bipolar Radiofrequency Combined with L-vitamin C in the Treatment of Facial Skin Photoaging[J].Medical Aesthetics and Beauty,2018,(5):94.
[3]文丽萍,周书帆,邓 映,等. 短波理疗联合强脉冲光治疗面部糖皮质激素依赖性皮炎临床观察[J].中国美容医学,2018,(11):36.
　WEN Li-ping,ZHOU Shu-fan,DENG Ying,et al. Clinical Observation of Desensitization Apparatus Combined with Intense PulsedLight in the Treatment of Facial Glucocorticosteroid-dependent Dermatitis[J].Medical Aesthetics and Beauty,2018,(5):36.
[4]华若岳. 重组人表皮生长因子在面部深Ⅱ度烧伤创面修复中的应用研究[J].中国美容医学,2019,(02):36.
　HUA Ruo-yue. Application of rhEGF in the Process of Facial Deep Second Degree Burn Wound Repair[J].Medical Aesthetics and Beauty,2019,(5):36.
[5]陈 燕,李 生,马 明. 强脉冲光联合长脉宽Nd:YAG激光治疗面部毛细血管扩张症疗效观察[J].中国美容医学,2019,(03):54.
　CHEN Yan,LI Sheng,MA Ming. Therapeutic Effect of Intense Pulsed Light Combined with Long Pulse Width Nd:YAGLaser on Facial Telangiectasia[J].Medical Aesthetics and Beauty,2019,(5):54.
[6]战大川,赵月荣,赵振德,等. bFGF联合自体脂肪移植在面部凹陷性瘢痕治疗中的美容价值研究[J].中国美容医学,2019,(04):116.
　ZHAN Da-chuan,ZHAO Yue-rong,ZHAO Zhen-de,et al. Study on the Cosmetic Value of bFGF Combined with Autologous Fat Transplantationin the Treatment of Facial Depressed Scar[J].Medical Aesthetics and Beauty,2019,(5):116.
[7]何航远,赵小瑜,韩 未,等. 面部皮脂腺囊肿小切口摘除术的诊疗探讨[J].中国美容医学,2019,(04):128.
　HE Hang-yuan,ZHAO Xiao-yu,HAN Wei,et al. Experience in Treatment of Facial Sebaceous Cyst with Small Incision Surgery[J].Medical Aesthetics and Beauty,2019,(5):128.
[8]丛 林,杨蓉娅. 贻贝提取物护理软膏治疗面部敏感性皮肤疗效观察[J].中国美容医学,2019,(05):47.
　CONG Lin,YANG Rong-ya. Clinical Efficacy of Mussel Adhesive Protein Extractive Ointment on Facial Sensitive Skin[J].Medical Aesthetics and Beauty,2019,(5):47.
[9]刘芃祥,王文娟,郝永红,等. 皮肤镜在面部光线性角化病诊断中的应用研究[J].中国美容医学,2019,(05):50.
　LIU Peng-xiang,WANG Wen-juan,HAO Yong-hong,et al. Application of Dermoscopy in the Diagnosis of Facial Actinic Keratosis[J].Medical Aesthetics and Beauty,2019,(5):50.
[10]陈永平,王金河. 点阵铒激光联合羟基乙酸治疗面部痤疮瘢痕临床观察[J].中国美容医学,2019,(06):56.
　CHEN Yong-ping,WANG Jin-he. Clinical Efficacy of Combined Lattice Erbium Laser with Glycolic Acid Treatment of Facial Acne Scar[J].Medical Aesthetics and Beauty,2019,(5):56.

更新日期/Last Update: 2024-05-11