[1]张 畅,吴乐昊,王佳琦. 纳米脂肪移植技术疗效的系统评价[J].中国美容医学,2019,(03):20-24.
　ZHANG Chang,WU Le-hao,WANG Jia-qi. Clinical Efficacy of Nanofat Grafting: A Systematic Review[J].Medical Aesthetics and Beauty,2019,(03):20-24.
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 纳米脂肪移植技术疗效的系统评价
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《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:
期数:
2019年03期
页码:
20-24
栏目:
出版日期:
2019-03-11

文章信息/Info

Title:
 Clinical Efficacy of Nanofat Grafting: A Systematic Review
文章编号:
1008-6455（2019）03-0020-05
作者:
张 畅; 吴乐昊; 王佳琦
Author(s):
ZHANG Chang; WU Le-hao; WANG Jia-qi
关键词:
[关键词]纳米脂肪移植; 瘢痕; 面部年轻化; 软组织凹陷; 随机对照试验; 病例报道; 系统评价
Keywords:
Key words: nanofat grafting;  scars;  facial rejuvenation;  soft tissue depression;  randomized controlled trials;  case report; systematic review
分类号:
R622
文献标志码:
A
摘要:
[摘要]目的：对纳米脂肪治疗瘢痕、皱纹、眶周衰老问题的临床疗效进行系统评价。方法：计算机检索PubMed、Embase数据
库、Cochrane 图书馆、The Cochrane Central Register of Controlled Trail（CENTRAL）、万方数据库、维普数据库和
中国知网，收集所有关于纳米脂肪在整形外科临床应用方面的随机对照试验和病例系列报道。结果：检获符合纳入条件的文
献共5个随机对照试验和6个病例系列报道。所有的研究结论均表明纳米脂肪在瘢痕和面部年轻化等方面的治疗具有有效性。
结论：由于受纳入文献的数量和质量的限制，对于纳米脂肪的疗效暂无法得出明确结论。纳入的研究在方法学上尚存在缺
陷，有必要设计更科学严谨的试验方案，开展更多、更高质量的随机对照试验来进一步支持这一结论。

Abstract:
Abstract: Objective To systematically review the literatures about clinical outcomes of nanofat grafting in the treatment of
scar, wrinkle and periorbital aging. Methods PubMed, Embase database, Cochrane Library, The Cochrane Central Register of
Controlled Trail (CENTRAL), Wanfang database, VIP database and CNKI were searched to collect randomized controlled trials
and case series about the clinical application of nanofat in plastic surgery. Results A total of 5 randomized controlled trials and
6 case series eligible for inclusion were collected. Based on the results of those trials, nanofat was effective in treating scars
and achieving facial rejuvenation. However, the qualities of the 5 randomized controlled trials were assessed as moderate and
high risk of bias,according to Cochrane Handbook Version 5.0. Conclusion Due to the limitations of the quantity and quality
of all the literatures included, the conclusion on the efficacy of nanofat is not clear. Methodologically,There are defects in the
included studies, thus, more rigorous trial protocols and more high quality randomized controlled trials are needed to further
support this conclusion.

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更新日期/Last Update: 2019-03-29