[1] 曹文娟,徐 远,章含奇,等. CO2激光联合重组人干扰素α-2b凝胶治疗面部扁平疣疗效分析[J].中国美容医学,2021,(8):57-59.
　 CAO Wen-juan,XU Yuan,ZHANG Han-qi,et al. Effect of CO2 Laser Combined with Recombinant Human Interferon α-2b Gel in theTreatment of Facial Verruca Plana[J].Medical Aesthetics and Beauty,2021,(8):57-59.
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 CO2激光联合重组人干扰素α-2b凝胶治疗面部扁平疣疗效分析
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《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:
期数:
2021年8期
页码:
57-59
栏目:
出版日期:
2021-08-10

文章信息/Info

Title:
 Effect of CO2 Laser Combined with Recombinant Human Interferon α-2b Gel in the
Treatment of Facial Verruca Plana
文章编号:
1008-6455(2021)-08-0057-03
作者:
 曹文娟; 徐 远; 章含奇; 刘 腾; 洪 莉
Author(s):
 CAO Wen-juan;  XU Yuan;  ZHANG Han-qi;  LIU Teng;  HONG Li
关键词:
 [关键词]皮肤病生活质量评分; 面部; 扁平疣; CO2激光; 重组人干扰素α-2b凝胶
Keywords:
Key words:verruca plana;  carbon dioxide laser;  recombinant human interferon α-2b gel;  efficacy;  dermatology life quality index
分类号:
R752.5+2
文献标志码:
A
摘要:
[摘要]目的：分析CO2激光联合重组人干扰素α-2b凝胶治疗面部扁平疣患者的疗效及对患者皮肤病生活质量评分的影响。方
法：选取2018年7月-2019年12月笔者科室收治的62例面部扁平疣患者。根据随机对照实验将患者分为研究组（31例）与对
照组（31例）。对照组采用CO2激光治疗，研究组给予重组人干扰素α-2b凝胶辅助CO2激光治疗。观察两组患者治疗效
果、皮肤病生活质量指数量表（DLQI）评分、不良反应率及复发率。结果：治疗后，研究组治疗有效率达93.55%，高
于对照组的70.97%，两组比较有显著性差异（P ＜0.05）；两组患者DLQI评分均降低，研究组低于对照组，具有统计学
意义（P ＜0.05）；研究组不良反应率及复发率均低于对照组，具有统计学意义（P ＜0.05）。结论：采用重组人干扰素α-2b
凝胶辅助CO2激光治疗面部扁平疣，能有效提高机体免疫能力，清除体内HPV病毒，降低并发症及复发率，临床疗效佳。

Abstract:
Abstract: Objective To explore the effect of carbon dioxide laser combined with recombinant human interferon α-2b
geltreatment on efficacy and dermatology life quality index (DLQI) score in patients with verruca plana. Methods A total of
62 patients with verruca plana admitted to the hospital from July 2018 to December 2019 were selected. According to the
randomized controlled experiments, patients were divided into study group (31 cases) and control group (31 cases). The
control group was treated with CO2 laser, and the study group received recombinant human interferon α-2b gel with CO2 laser
treatment. Efficacy, dermatology life quality index (DLQI) score, adverse reaction rate and recurrence rate of the two groups
of patients were recorded. Results The total effective rate of treatment was higher in the study group than in the control group
(93.55% vs. 70.97%, P ＜0.05). After treatment, the DLQI scores of the two groups of patients decreased and were lower in the
study group than in the control group (P ＜0.05). The adverse reaction rate and the recurrence rate of the study group were lower
than those of the control group (P ＜0.05). Conclusion The application of recombinant human interferon α-2b gel with CO2
laser in verruca plana can effectively improve the body’s immunity, remove HPV virus from the body, reduce complications and
recurrence rates, with good efficacy.

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更新日期/Last Update: 2021-09-07