[1]王士成,马靖雯,史学然,等.臭氧油抗菌剂治疗慢性牙周炎的疗效及对龈下菌群的影响[J].中国美容医学,2022,(4):140-143.
　WANG Shicheng,MA Jingwen,SHI Xueran,et al.Clinical Efficacy of Ozone Oil Antibacterial Agent on Chronic Periodontitis and Its Effects on Subgingival Microflora[J].Medical Aesthetics and Beauty,2022,(4):140-143.
点击复制

臭氧油抗菌剂治疗慢性牙周炎的疗效及对龈下菌群的影响()
分享到：

《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:
期数:
2022年4期
页码:
140-143
栏目:
出版日期:
2022-04-10

文章信息/Info

Title:
Clinical Efficacy of Ozone Oil Antibacterial Agent on Chronic Periodontitis and Its Effects on Subgingival Microflora
文章编号:
1008-6455(2022)04-0140-03
作者:
王士成1; 马靖雯2; 史学然3; 王立莹1; 刘善忠1
(1.廊坊市人民医院口腔科 河北 廊坊 065099 ;2.廊坊市安次区医院口腔科 河北 廊坊 065012 ;3.廊坊爱嘉口腔门诊部口腔科 河北 廊坊 065000)
Author(s):
WANG Shicheng1; MA Jingwen 2; SHI Xueran3; WANG Liying1; LIU Shanzhong1
(1.Department of Stomatology, Langfang People’s Hospital, Langfang 065099,Hebei,China; 2. Department of Stomatology, Anzi District Hospital, Langfang 065012, Hebei,China; 3.Department of Stomatology,Aijia Dental Clinic, Langfang 065000,Hebei,China)
关键词:
慢性牙周炎; 臭氧油; 治疗效果; 龈下菌群; 微生物; 多样性
Keywords:
chronic periodontitis;  ozone oil;  therapeutic effect;  subgingival microflora;  microbial;  diversity
分类号:
R781.4+2
文献标志码:
A [
摘要:
目的：探讨臭氧油抗菌剂治疗慢性牙周炎的疗效及对龈下菌群的影响。方法：按照随机数字表法将2019年1月-12月笔者医院口腔科收治的200例慢性牙周炎患者分为对照组和观察组，每组100例。对照组患者给予龈下刮治术，观察组患者在此基础上加用臭氧油抗菌剂，治疗4周。比较治疗前及治疗后6周、12周两组的菌斑指数(PLI)、牙龈指数(GI)、探诊深度(PD)和附着丧失(AL)；于治疗前及治疗后6周、12周对龈下菌斑16SrDNA进行PCR后行琼脂糖凝胶电泳，分析菌群种类及含量。结果：治疗后6、12个月，观察组的PLI、GI、PD、AL均低于对照组，差异均具有统计学意义(P＜0.05)；治疗前，观察组与对照组分别发现27种与28种菌群，治疗后6、12个月，观察组与对照组分别发现5种与9种菌群，观察组的牙龈卟啉单胞菌、伴放线菌嗜血菌、福赛斯坦纳菌、中间普雷沃菌、齿垢密螺旋体含量低于对照组，差异均具有统计学意义(P＜0.05)。结论：臭氧油抗菌剂治疗慢性牙周炎的疗效明显，对慢性牙周炎致病菌具有很好的杀灭作用。
Abstract:
Objective To discuss the clinical efficacy of ozone oil antibacterial agent on chronic periodontitis and its effects on subgingival microflora. Methods According to the random number method, 200 patients with chronic periodontitis who were divided into control group and observation group in the stomatology department of our hospital from January to December 2019,100 patients in each group. Patients were treated with subgingival curetry in the control group, and patients were treated with ozone oil antibacterial agent on the subgingival curetry in the observation group, all the patients were treated for 4 weeks. The plaque index (PLI), gingival index (GI), probing depth (PD), and attachment loss (AL) was compared between two groups before and 6, 12 weeks after treatment. After PCR on subgingival plaque 16S rDNA, agarose gel electrophoresis was performed to analyze the species and contents of bacteriabefore and 6 and 12 weeks after treatment. Results At 6 and 12 months after treatment, PLI, GI, PD and AL in the observation group was all lower than those in the control group, with statistically significant differences(P＜0.05). Before treatment, 27 and 28 strains of bacteria were found in the observation group and the control group,respectively. 5 and 9 strains were found in the observation group and the control group at 6 and 12 months after treatment, respectively. The contents of Porphyromonas gingiva, Haemophilus actinomycete,Forsystana,Prevotella intermediate and Treponema pallidus in the observation group were lower than those in the control group, with statistically significant differences(P＜0.05). Conclusion Ozone oil antibacterial agent was effective in the treatment of chronic periodontitis and it had a good killing effect on the pathogenic bacteria of chronic periodontitis.

相似文献/References:

[1]查建鑫,李长青. 微型种植体支抗在慢性牙周炎口腔正畸中的应用[J].中国美容医学,2018,(05):101.
　ZHA Jian-xin,LI Chang-qing. Clinical Application of Mini Implant Anchorage in Periodontal Orthodontics[J].Medical Aesthetics and Beauty,2018,(4):101.
[2] 叶 眉,李 峥,张 晨,等. 龈下超声洁治结合甘氨酸龈下喷砂对慢性牙周炎临床指标的影响[J].中国美容医学,2020,(6):129.
　 YE Mei,LI Zheng,ZHANG Chen,et al. Effect of Subgingival Glycine Air Polishing Combined with SubgingivalSandblasting on the Clinical Parameters of Chronic Periodontitis[J].Medical Aesthetics and Beauty,2020,(4):129.
[3] 黄海荣,王文鹏,楚艺婷. 清胃固齿方辅助治疗慢性牙周炎的疗效以及对龈沟液MMPs/TIMP表达的影响[J].中国美容医学,2020,(11):142.
　 HUANG Hai-rong,WANG Wen-peng,CHU Yi-ting. Effi cacy of Qingwei Guding Prescription in Treating Chronic Periodontitis and ItsEffect on Gingival Crevicular Fluid Levels of MMPs/TIMP[J].Medical Aesthetics and Beauty,2020,(4):142.
[4] 周琦琪,韩祥祯,张文静,等. 全唾液法分析糖尿病及牙周炎伴牙列缺损患者行种植义齿修复的临床效果[J].中国美容医学,2021,(1):104.
　 ZHOU Qi-qi,HAN Xiang-zhen,ZHANG Wen-jing,et al. Analysis of the Clinical Effect of Complete Saliva Analysis on the Repair of DentalImplant Denture in Patients with Diabetes and Periodontitis with Dentition Defect[J].Medical Aesthetics and Beauty,2021,(4):104.
[5] 王贯新,马 睿. 隐形矫治对成人中度慢性牙周炎患者牙周指标及唇侧外观的影响[J].中国美容医学,2021,(4):129.
　 WANG Guan-xin,MA Rui. Effect of Invisalign on Root Length, Alveolar Bone Height and Labial Appearance inAdults with Moderate Chronic Periodontitis[J].Medical Aesthetics and Beauty,2021,(4):129.
[6] 韩 炎,王俊华,周丽芝. 牙周基础治疗对2型糖尿病合并慢性牙周炎患者糖脂代谢及炎症反应的影响[J].中国美容医学,2021,(6):136.
　 HAN Yan,WANG Jun-hua,ZHOU Li-zhi. Effects of Periodental Non-surgical Treatment on Glycolipid Metabolism andInflammatory Response in Patients with Type 2 Diabetes Mellitus Complicated withChronic Periodontitis[J].Medical Aesthetics and Beauty,2021,(4):136.
[7] 李瑛琦 张煜培 王晨茜 翟佳雪 唐成芳 综述,曾 辉 审校. 慢性牙周炎的中医药治疗研究进展[J].中国美容医学,2021,(10):178.
　 LI Ying-qi,ZHANG Yu-pei,WANG Chen-qian,et al. Research Progress of Chronic Periodontitis in Traditional Chinese Medicine[J].Medical Aesthetics and Beauty,2021,(4):178.
[8]郭 欣,喻书琛,李美文,等.吲哚菁绿介导的光动力疗法对牙周炎疗效的Meta分析[J].中国美容医学,2022,(1):111.
　GUO Xin,YU Shushen,LI Meiwen,et al.The Effect of Indocyanine Green-mediated Photodynamic Therapy in Treating Periodontitis: A Meta-analysis[J].Medical Aesthetics and Beauty,2022,(4):111.
[9]郭建茹,高志强,冯 妍,等.富血小板纤维蛋白联合GTR对慢性牙周炎牙槽骨垂直吸收患牙牙周软硬组织的修复效果研究[J].中国美容医学,2022,(5):137.
　GUO Jianru,GAO Zhiqiang,FENG Yan,et al.Effect of Platelet Rich Fibrin Combined with GTR on Periodontal Soft and Hard Tissue in Patients with Vertical Alveolar Bone Resorption in Chronic Periodontitis[J].Medical Aesthetics and Beauty,2022,(4):137.
[10]郭建茹,冯 妍,娄会杰,等.PRF联合龈下刮治、根面平整术治疗慢性牙周炎临床效果分析[J].中国美容医学,2022,(8):160.
　GUO Jianru,FENG Yan,LOU Huijie,et al.The Clinical Effect Analysis of PRF Combined with Subgingival Scaling and Root Planing in the Treatment of Chronic Periodontitis[J].Medical Aesthetics and Beauty,2022,(4):160.

更新日期/Last Update: 2022-05-07