[1] 罗 倩,严妮娜,郝 瑜. 新型强脉冲光联合氨甲环酸治疗黄褐斑临床研究[J].中国美容医学,2021,(3):27-30.
　 LUO Qian,YAN Ni-na,HAO Yu. Clinical Study on the Treatment of Melasma with A New Type Intense Pulsed LightCombined with Tranexamic Acid[J].Medical Aesthetics and Beauty,2021,(3):27-30.
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 新型强脉冲光联合氨甲环酸治疗黄褐斑临床研究
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《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:
期数:
2021年3期
页码:
27-30
栏目:
出版日期:
2021-03-10

文章信息/Info

Title:
 Clinical Study on the Treatment of Melasma with A New Type Intense Pulsed Light
Combined with Tranexamic Acid
文章编号:
1008-6455（2021）03-0027-03
作者:
 罗 倩; 严妮娜; 郝 瑜
Author(s):
 LUO Qian;  YAN Ni-na;  HAO Yu
关键词:
 [关键词]新型强脉冲光; 氨甲环酸; 黄褐斑; 联合治疗
Keywords:
 Key words:new type intense pulsed light;  tranexamic acid;  melasma;  combination theropy;  clinical research
分类号:
R758.4+2
文献标志码:
A
摘要:
[摘要]目的：探讨具有完美脉冲技术(Optimal pulse technology,0PT)的新型强脉冲光(Intense pulsed light,IPL)联合氨
甲环酸治疗黄褐斑的临床疗效及安全性。方法：选取2017年9月-2019年5月笔者科室就诊的90例黄褐斑患者，随机分成实验
组和对照组，每组45例。实验组用新型强脉冲光联合氨甲环酸治疗，对照组仅使用新型强脉冲光治疗。治疗期间及疗程结
束后1个月，评价疗效和不良反应。结果：实验组显效率为68.89%，总有效率93.33%；对照组显效率为33.33%，总有效率为
68.89%。两组仅有个别病例出现轻微不良反应。结论：新型强脉冲光联合氨甲环酸治疗黄褐斑安全可靠、操作便捷、无创
伤，且能显著改善皮肤光老化的多种状态（皮肤暗沉、皮肤粗糙、细小皱纹、毛细血管扩张及毛孔粗大），使皮肤质地较以
前更光滑、细致。

Abstract:
Abstract: Objective In order to the clinical analysis and safty of the therapeutic effect of tranexamic acid combined with
intense pulsed light(IPL) incorporated with optimal pulse technology (OPT) treatment of chloasma. Methods From September
2017 to May 2019, 90 patients with chloasma were selected, they were randomly divided into experimental group and control
group, 45 cases each, the experimental group were treated with IPL-OPT combined with oral tranexamic, for treatment of the
control group were treated with IPL-OPT. During the treatment period and one month after the treatment course to evaluate the
efficacy and observe the adverser eactions. Results The apparent efficiency of the experimental group was 68.89%, the total
effective rate was 93.33%, and that of the control group was 33.33%, the total effective rate was 68.89%. Minor adverse events
occurred in two groups. Conclusion The treatment of melasma with IPL-OPT combined with oral tranexamic is safe, reliable,
convenient, noninvasive, and can significantly improve the various state of skin photoaging(skin dull ,roughness, fine wrinkles,
telangiectasis, pores thick), making skin texture smoother and more meticulous than before , without the advantage of vacation,
suitable for the pace of modern life.

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更新日期/Last Update: 2021-04-13