[1]肖俊文,高 旋,杨 光.氢氧化钙和替硝唑联合浓缩生长因子治疗年轻恒牙牙髓坏死或根尖周炎疗效观察[J].中国美容医学,2024,(2):146-149.[doi:10.15909/j.cnki.cn61-1347/r.006131]
　XIAO Junwen,GAO Xuan,YANG Guang.Clinical Observation of Calcium Hydroxide, Tinidazole and Concentrated Growth Factor in the Treatment of Pulp Necrosis or Periapical Periodontitis of Young Permanent Teeth[J].Medical Aesthetics and Beauty,2024,(2):146-149.[doi:10.15909/j.cnki.cn61-1347/r.006131]
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氢氧化钙和替硝唑联合浓缩生长因子治疗年轻恒牙牙髓坏死或根尖周炎疗效观察()
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《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:
期数:
2024年2期
页码:
146-149
栏目:
出版日期:
2024-02-10

文章信息/Info

Title:
Clinical Observation of Calcium Hydroxide, Tinidazole and Concentrated Growth Factor in the Treatment of Pulp Necrosis or Periapical Periodontitis of Young Permanent Teeth
文章编号:
1008-6455（2024）02-0146-04
作者:
肖俊文1 ; 高 旋2 ; 杨 光2
(1.武汉市第九医院口腔科 湖北 武汉 430081 ;2.武汉东西湖高旋口腔科诊所 湖北 武汉 430081 )
Author(s):
XIAO Junwen1 ; GAO Xuan2 ; YANG Guang2
( 1.Department of Stomatology,Wuhan Ninth Hospital,Wuhan 430081,Hubei,China; 2.Wuhan Dongxihu High Rotation Stomatological Clinic,Wuhan 430081,Hubei,China)
关键词:
根管消毒; 浓缩生长因子; 年轻恒牙; 牙髓坏死; 血运重建术
Keywords:
root canal disinfection;  concentrated growth factors;  young permanent teeth;  pulp necrosis;  pulp revascularization
分类号:
R781.4+ 2
DOI:
10.15909/j.cnki.cn61-1347/r.006131
文献标志码:
A
摘要:
目的：观察氢氧化钙、替硝唑联合浓缩生长因子治疗年轻恒牙牙髓坏死或根尖周炎的疗效。方法：将2019年7月-2021 年4月笔者医院诊治的86例单根管年轻恒牙牙髓坏死或根尖周炎患儿按随机数字表法分为常规组[n=43，采用牙髓血运重 建术（Pulp revascularization，PR），其中的根管消毒环节应用氢氧化钙、替硝唑]和浓缩生长因子组（n =43， 在常规组基础上加用浓缩生长因子）。术后12个月复查判定两组疗效，并比较两组管壁厚、根长、咀嚼效能（咬合力和 咀嚼效率）和牙骨样组织沉积率。结果：浓缩生长因子组总有效率为95.35%，常规组为81.40%，组间比较差异有统计学 意义（P＜0.05）；术后12个月，两组根管壁均较术前增厚，根长均较术前明显增加（P＜0.05），咬合力、咀嚼效率均 较术前明显增高（P＜0.05），且浓缩生长因子组根管壁明显较常规组厚、根长明显较常规组长（P＜0.05），咬合力、咀嚼 效率明显较常规组高（P＜0.05）；浓缩生长因子组术后6个月、12个月牙骨样组织沉积率均明显较常规组高（P＜0.05）。结 论：在牙髓坏死或根尖周炎患者PR中采用氢氧化钙、替硝唑联合浓缩生长因子，可明显提高牙骨样组织沉积率，能有效促进 根管生长及患牙功能恢复。
Abstract:
Objective To observe the curative eff ect of calcium hydroxide and tinidazole combined with concentrated growth factor on pulp necrosis or periapical periodontitis of young permanent teeth. Methods From July 2019 to April 2021, 86 young children with permanent tooth pulp necrosis or apical periodontitis diagnosed and treated in author’s hospital were grouped into the routine group [n=43, application of calcium hydroxide and tinidazole in root canal disinfection in pulp revascularization (PR)] and concentrated growth factor group (n=43, concentrated growth factor was added on the basis of routine group) according to the random number table method. At 12 months after the operation, the curative eff ect of the two groups was judged, and the wall thickness, root length, masticatory effi ciency [bite force, masticatory effi ciency] and the deposition rate of cementum-like tissue were compared between the two groups. Results The total eff ective rate was 95.35% in the concentrated growth factor group and 81.40% in the routine group, there was a obvious difference between the groups (P ＜0.05); at 12 months after operation, the root canal wall in both groups was thicker than that before operation (P＜0.05), the root length was obviously increased (P＜0.05), and the occlusal force and chewing effi ciency were obviously higher than those before operation (P ＜0.05), and the root canal wall in the concentrated growth factor group was obviously thicker than that in the conventional group (P＜0.05), the root length was obviously longer than that in the conventional group (P＜0.05), and the occlusal force and chewing effi ciency were obviously higher than those in the conventional group (P ＜0.05). The deposition rates of cementoid tissue at 6 and 12 months in the concentrated growth factor group were obviously higher than those in the conventional group (P ＜0.05). Conclusion The combination of calcium hydroxide and tinidazole concentration of growth factor in PR of patients with pulp necrosis or periapical infl ammation can signifi cantly improve the deposition rate of bone tissue, eff ectively promote the growth of root canal and functional recovery of aff ected teeth.

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更新日期/Last Update: 2024-02-27