[1]王春贵,张宝林.手术切除联合放疗与博来霉素注射治疗耳廓瘢痕疙瘩疗效对比[J].中国美容医学,2018,(06):71-74.
　WANG Chun-gui,ZHANG Bao-lin. Comparison of Curative Effect between Combined Radiotherapy and Bolamycin Injection after Auricle Keloid Resection[J].Medical Aesthetics and Beauty,2018,(06):71-74.
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手术切除联合放疗与博来霉素注射治疗耳廓瘢痕疙瘩疗效对比
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《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:
期数:
2018年06期
页码:
71-74
栏目:
出版日期:
2018-07-10

文章信息/Info

Title:
 Comparison of Curative Effect between Combined Radiotherapy and Bolamycin Injection after Auricle Keloid Resection
文章编号:
1008-6455(2018)06-0071-04
作者:
王春贵1; 2; 张宝林3
Author(s):
WANG Chun-gui1; 2; ZHANG Bao-lin3
关键词:
[关键词]耳廓; 瘢痕疙瘩; Sawada（1990）量表; 放射治疗; 博来霉素注射治疗
Keywords:
Key words: ear;  keloid;  sawada(1990) keloid score scale;  radiotherapy;  intralesional bleomycin injection
分类号:
R619+.6
文献标志码:
A
摘要:
[摘要]目的：探讨不同临床分级耳廓瘢痕疙瘩切除术后联合放射治疗与联合博来霉素注射治疗的疗效差异。方法：采用
Sawada量表对纳入的156例耳廓瘢痕疙瘩患者进行分级，随机分为单纯手术切除组、手术切除联合放疗组、手术切除联合
博来霉素注射组，治疗后随访1年，依据Darzi的瘢痕疙瘩疗效标准判断疗效，并进行统计学分析。结果：对于本研究纳入
的所有患者，手术切除联合放疗的有效率为90.4%，手术切除联合博来霉素注射的有效率为83.7%，单纯手术切除的有效率
为59.6%；手术组疗效明显低于联合放疗组及联合博来霉素注射组（P ＜0.01）；而联合放疗组与联合博来霉素注射组相
比，疗效比较差异无统计学意义（P ＞0.05）。对于轻度、重度耳廓瘢痕疙瘩患者，经组间χ2检验，手术组与其他两组疗
效比较，差异无统计学意义（P ＞0.05）；对于中度的耳廓瘢痕疙瘩患者，经组间χ2检验，手术组疗效明显低于其他两组
（P ＜0.01）。结论：在耳廓瘢痕疙瘩治疗中，单纯手术切除疗效较差，对于中度的耳廓瘢痕疙瘩患者，手术切除联合放射
治疗与手术切除联合博来霉素注射治疗总体满意，可以根据具体情况个性化使用。
Abstract:
Abstract: Objecctive To investigate the difference of therapeutic effect between combined radiotherapy and bolamycin
injection after different clinical stages of auricle keloid resection. Methods Sawada scale in 156 cases of keloid patients for
classification of auricle, were randomly divided into simple surgical excision group, surgical resection combined radiotherapy
group, the surgical removal of the joint bleomycin injection group, followed up for 1 year, according to the standard judging
curative effect Darzi keloid curative effect, and statistical analysis. Results For all patients included in this study, the effective
rate of surgical resection combined with radiotherapy was 90.4%, that of surgical resection combined with bleomycin injection
was 83.7%, and that of surgical resection alone was 59.6%.The efficacy of operation group was significantly lower than that of
radiotherapy group and borai group (P ＜0.01).The difference in curative effect between the radiotherapy group and the borai
group was not statistically significant (P ＞0.05). For patients with mild and severe auricular keloid, there was no statistically
significant difference between the surgical group and the other two groups (P ＞0.05).For patients with moderate auricular
keloid, the efficacy of the surgical group was significantly lower than that of the other two groups (P ＞0.01). Conclusion In
keloid treatment of auricle, simple surgical removal of the curative effect is poor, for moderate auricle keloids, surgical removal
of combined radiotherapy and surgery with bleomycin injection therapy overall satisfaction, can be used according to the
specific situation personalized.

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更新日期/Last Update: 2018-08-09