[1]孙 静 陈双瑜 综述,杨 婷 审校.基底膜带受损在黄褐斑发病机制中的作用[J].中国美容医学,2024,(10):187-190.
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基底膜带受损在黄褐斑发病机制中的作用()
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《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:
期数:
2024年10期
页码:
187-190
栏目:
出版日期:
2024-09-26

文章信息/Info

文章编号:
1008-6455（2024）10-0187-04
作者:
孙 静1 陈双瑜2 综述; 杨 婷3 审校
(1.成都市郫都区人民医院皮肤科 成都医学院第三附属医院 四川 成都 611730;2.成都高新米兰柏羽医学美容医院皮肤美容 科 四川 成都 610095;3.四川大学华西口腔医院医疗美容科 四川 成都 610041)
关键词:
黄褐斑; 发病机制; 基底膜带; 悬垂黑素细胞; IV型胶原蛋白
Keywords:
melasma;  pathogenesis;  basement membrane zone;  pendulous melanocytes;  type IV collagen
分类号:
R758.4+ 2
文献标志码:
A
摘要:
黄褐斑是一种好发于面部日光暴露部位的获得性色素沉着性疾病。其治疗方式多样，各种治疗结局差异很大以及治疗 后的复发率居高不下是黄褐斑目前治疗的最大困难。近年来，有学者逐渐认识到黄褐斑皮损处基底膜带受损可能是其重要发 病机制之一，本文收集了近年来关于黄褐斑皮损处基底膜带受损的相关研究，并列举了有关修复皮肤基底膜带从而达到治疗 黄褐斑的一些方法，为黄褐斑治疗提供新的选择，有望为降低黄褐斑的复发率提供新的参考依据。
Abstract:
Melasma is an acquired pigmentation disease that often occurs in the exposed parts of the face. Management of melasma is highly challenging due to inconsistent treatment results and frequent relapses. Researchers have gradually realized that the damage of basement membrane zone(BMZ) may be an important pathogenesis of melasma. Herein, we collected the evidence of the damage of basement membrane zone in melasma, listed some methods of recovery the basement membrane zone. Our data suggest that ameliorating the basement membrane zone may be of great signifi cance in the treatment of melasma and the prevention of recurrence.

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更新日期/Last Update: 2024-10-10