[1] 胡太平,陶剑光,李大鹏,等. 超声导入曲安奈德联合微等离子体射频技术对增生性瘢痕患者瘢痕组织学的影响[J].中国美容医学,2021,(8):68-71.
　 HU Tai-ping,TAO Jian-guang,LI Da-peng,et al. The Effect of Ultrasonic Importing Triamcinolone Acetonide Combined MicroplasmaRadiofrequency on Scar Histology in the Patients with Hypertrophic Necrosis[J].Medical Aesthetics and Beauty,2021,(8):68-71.
点击复制

 超声导入曲安奈德联合微等离子体射频技术对增生性瘢痕患者瘢痕组织学
的影响
()
分享到：

《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:
期数:
2021年8期
页码:
68-71
栏目:
出版日期:
2021-08-10

文章信息/Info

Title:
 The Effect of Ultrasonic Importing Triamcinolone Acetonide Combined Microplasma
Radiofrequency on Scar Histology in the Patients with Hypertrophic Necrosis
文章编号:
1008-6455(2021)08-0068-04
作者:
 胡太平1; 陶剑光2; 李大鹏1; 周丽娟1; 刘菲菲1
Author(s):
 HU Tai-ping1; TAO Jian-guang2; LI Da-peng1; ZHOU Li-juan1; LIU Fei-fei1
关键词:
 [关键词]增生性瘢痕; 曲安奈德; 超声导入; 微等离子体射频技术; 温哥华瘢痕评分量化表; 组织学
Keywords:
 Key words: hyperplastic scar;  triamcinolone acetonide;  ultrasonic introduction;  local electron-beam radiation therapy; vancouver scar scale;  histology
分类号:
R619+.6
文献标志码:
A
摘要:
[摘要]目的：探究超声导入曲安奈德联合微等离子体射频技术对增生性瘢痕患者的瘢痕修复效果。方法：选择2016年3
月-2019年5月笔者医院医学美容科和烧伤整形科收治的90例增生性瘢痕患者，通过随机数字表法分为对照组（n =45）和观察
组（n=45）。两组均予以微等离子体射频技术治疗，观察组在此基础上予以超声导入曲安奈德进行治疗。比较两组疼痛及瘙
痒症状、瘢痕恢复情况、心理状况、疗效、不良反应及瘢痕组织学特征变化。结果：治疗后，两组温哥华瘢痕评分量化表
（VSS）、疼痛、瘙痒评分较治疗前降低，且观察组低于对照组（P ＜0.05）。治疗后，观察组患者的焦虑、抑郁评分较治疗
前降低，主观幸福感评分较治疗前升高（P ＜0.05）；对照组患者的抑郁评分较治疗前降低（P ＜0.05），观察组焦虑、抑郁
评分低于对照组，主观幸福感评分高于对照组（P ＜0.05）。观察组总有效率为91.11%，高于对照组的66.67%（P ＜0.05）。
组织学观察结果显示，治疗后观察组相较对照组瘢痕组织表皮恢复更为显著，真皮浅层成纤维细胞及胶原纤维数量更少且排
列相对规整。观察组、对照组仅发生色素沉着，分别为3例（6.67%）、5例（11.11%），不良反应发生率比较无统计学差异
（P ＞0.05）。结论：在微等离子体射频技术的基础上予以超声导入曲安奈德可有效修复增生性瘢痕患者瘢痕状态，改善瘢
痕组织学特征，减轻患者疼痛瘙痒症状，进而改善其负性心理，值得临床推广使用。

Abstract:

Abstract:Objective To investigate the effect of ultrasonic importing triamcinolone acetonide combined microplasma
radiofrequency on scar histology in the patients with hypertrophic necrosis. Methods Between March 2016 and May 2019,
90 patients with hypertrophic necrosis were randomly divided into the control group (n =45) and the observation group
(n =45). The two groups were treated with microplasma radiofrequency, and the observation group was treated with ultrasonic
importing triamcinolone acetonide.The symptoms of pain and pruritus, scar recovery, psychological status, scar histology,
adverse reactions and curative effect were compared between the two groups. Results After the treatment, the scores of the
vancouver scar scale (VSS), pain and itching in the two groups were lower than that before the treatment, and those in the
observation group were lower than that in the control group (P ＜0.05). After treatment, the scores of anxiety and depression in
the observation group were lower than those before treatment, the scores of subjective well-being was higher than that before
treatment (P ＜0.05), the score of depression in the control group was lower than that before treatment (P ＜0.05), the scores of
anxiety and depression in the observation group were lower than those in the control group, and the scores of subjective wellbeing
in the observation group were higher than those in the control group (P ＜0.05). The results of the histological observation
show that the skin of the dermal fibroblast and the collagen fibers in the dermis is less and the arrangement is relatively regular
compared with that of the control group compared with the control group. The total effective rate in the observation group was
91.11% higher than that in the control group (66.67%, P ＜0.05). Only 3 cases (6.67%) and 5 cases (11.11%) of pigmentation
occurred in the observation group and the control group respectively, and there was no statistical difference in the incidence
of adverse reactions (P ＞0.05). Conclusion On the basis of microplasma radiofrequency, ultrasonic importing triamcinolone
acetonide can effectively repair the scar of patients with hypertrophic necrosis, improve that histological characteristic of the
scar, reduce the pain and itching symptoms of patients, and then improve their negative psychology, which is worthy for clinical
application.

相似文献/References:

[1]杨艳华.庆大霉素辅助局部注射修复眼睑炎性肉芽肿的美容效果及预后观察[J].中国美容医学,2018,(11):122.
　YANG Yan-hua.Clinical Observation of Eyelid Inflammatory Granuloma Treated by Gentamicin Assisted Local Injection[J].Medical Aesthetics and Beauty,2018,(8):122.
[2]蒋 丹,张长风,郭 鱼,等. 弹力压迫硅胶喷剂外用联合曲安奈德注射治疗烧伤后瘢痕增生的效果观察[J].中国美容医学,2019,(01):39.
　JIANG Dan,ZHANG Chang-feng,GUO Yu,et al. Effect of Elastic Compression Plus Silicone Spray Combined with TriamcinoloneAcetonide Injection on Scar Hyperplasia after Burn[J].Medical Aesthetics and Beauty,2019,(8):39.
[3]刘 艳,马晓蕾. 曲安奈德联合点阵激光及乳膏外涂序贯治疗增生性瘢痕的近远期疗效观察[J].中国美容医学,2019,(03):76.
　LIU Yan,MA Xiao-lei. Short-term and Long-term Effects of Triamcinolone Acetonide, Dot Laser and Creamin the Treatment of Scar Hyperplasia[J].Medical Aesthetics and Beauty,2019,(8):76.
[4]葛 锐,袁 艳.复方肝素钠尿囊素凝胶联合曲安奈德治疗瘢痕疙瘩疗效研究[J].中国美容医学,2019,(07):30.
　GE Rui,YUAN Yan. Curative Effect of Compound Heparin Sodium Allantoic Gel Combined with Triamcinolone Acetonide on Patients with Keloid[J].Medical Aesthetics and Beauty,2019,(8):30.
[5]宋慧丽,王玉霞,李 健,等. 曲安奈德联合利多卡因皮损内注射治疗苔藓样皮肤淀粉样变的疗效研究[J].中国美容医学,2019,(08):62.
　SONG Hui-li,WANG Yu-xia,LI Jian,et al. Therapeutic Effect of Intradermal Injection of Triamcinolone Acetonide andLidocaine for Mossy Amyloidosis Lesions[J].Medical Aesthetics and Beauty,2019,(8):62.
[6]王瑜玲,罗 东. 瘢痕组织瓣修复术联合曲安奈德注射治疗耳廓瘢痕疙瘩[J].中国美容医学,2019,(08):91.
　WANG Yu-ling,LUO Dong. Clinical Effect of Scar Tissue Flap Repair Combined with Triamcinolone AcetonideInjection in the Treatment of Auricle Keloid[J].Medical Aesthetics and Beauty,2019,(8):91.
[7]张 怡,赵小晖,吴信峰. 注射用A型肉毒毒素联合曲安奈德加5-FU联合注射在下颌角增生性瘢痕中的应用[J].中国美容医学,2019,(12):53.
　ZHANG Yi,ZHAO Xiao-hui,WU Xin-feng. Application of Injection of Botulinum Toxin Type A Combined with TriamcinoloneAcetonide Plus 5-FU in Injection for Mandibular Angle Scar[J].Medical Aesthetics and Beauty,2019,(8):53.
[8]陈 诚,余睿芳,张宝林. 无针注射器治疗瘢痕疙瘩的疗效研究[J].中国美容医学,2020,(3):82.
　CHEN Cheng,YU Rui-fang,ZHANG Bao-lin. Clinical Study on Needle-free Syringe (Injector) in the Treatment of Keloid[J].Medical Aesthetics and Beauty,2020,(8):82.
[9] 羊乃康,孙 琦. A型肉毒毒素与曲安奈德治疗瘢痕疙瘩的疗效和安全性比较[J].中国美容医学,2020,(5):66.
　 YANG Nai-kang,SUN Qi. Comparison of Effi cacy and Safety Between Botulinum Toxin Type A andTriamcinolone Acetonide in the Treatment of Keloid[J].Medical Aesthetics and Beauty,2020,(8):66.
[10] 张 玲,张绚辉,张杨梅,等. CO2点阵激光联合曲安奈德注射液封包治疗稳定期白癜风临床疗效评价[J].中国美容医学,2020,(8):62.
　 ZHANG Ling,ZHANG Xuan-hui,ZHANG Yang-mei,et al. Clinical Effi cacy Evaluation of CO2 Lattice Laser Combined with TriamcinoloneAcetonide Injection Packet in the Treatment of Vitiligo in Stable Phase[J].Medical Aesthetics and Beauty,2020,(8):62.
[11] 肖芳玲 综述,谭 军 审校. 增生性瘢痕的药物治疗进展[J].中国美容医学,2021,(4):181.
　 XIAO Fang-ling,TAN Jun. Advances in Drug Treatment For Hypertrophic Scar[J].Medical Aesthetics and Beauty,2021,(8):181.

更新日期/Last Update: 2021-09-07