[1]刘小青,才 琴,曹 静,等.10例面部黑素瘤患者的临床与病理分析[J].中国美容医学,2021,(12):82-85.
　LIU Xiao-qing,CAI Qin,CAO Jing,et al.Clinical and Pathological Analysis of 10 Patients with Facial Melanoma[J].Medical Aesthetics and Beauty,2021,(12):82-85.
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10例面部黑素瘤患者的临床与病理分析()
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《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:
期数:
2021年12期
页码:
82-85
栏目:
出版日期:
2021-12-10

文章信息/Info

Title:
Clinical and Pathological Analysis of 10 Patients with Facial Melanoma
文章编号:
1008-6455（2021）12-0082-04
作者:
刘小青1; 2; 才 琴2; 曹 静2; 樊俊威2; 边 毅2; 万学峰2
[1.苏州市独墅湖医院(苏州大学附属独墅湖医院)
Author(s):
LIU Xiao-qing1; 2; CAI Qin2; CAO Jing2; FAN Jun-wei2; BIAN Yi2; WAN Xue-feng2
(1.Department of Dermatology,Suzhou Dushu Lake Hospital( Dushu Lake Hospital Affiliated to Suzhou University),Suzhou 215125,Jiangsu,China;2.Department of Dermatology, the First Affiliated Hospital of Xinjiang Medical University,Urumqi 830054,Xinjiang,China]
关键词:
面部; 黑素瘤; 临床病理; 慢Mohs显微描记手术
Keywords:
facial;  melanoma;  flinicopathology;  slow Mohs micrographic surgery
分类号:
R739.5
文献标志码:
A
摘要:
目的：探讨面部黑素瘤的临床病理特点及其手术治疗。方法：回顾性分析10例在新疆医科大学第一附属医院皮肤科确诊的面部黑素瘤病例，于笔者医院皮肤科行慢Mohs显微描记手术，收集患者的临床病理资料及治疗情况。结果：面部黑素瘤在临床上通常表现为边界不清楚的斑片、其上可见大小不等的丘疹、结节，部分结节表面可见破溃；在组织病理上表现为表皮萎缩，表真皮交界处或真皮浅中层可见成巢或散在异形黑素细胞，沿基底层水平生长，真皮浅中层可见日光弹力纤维变性；采用慢Mohs显微描记手术一次性手术切净率低，甚至需要2～3次扩切，才能达到肿瘤的完全清除。结论：面部黑素瘤患者的皮损位于曝光部位，边界不清，皮肤萎缩明显，根据Breslow厚度确定手术扩切范围时，一次性切净率仅有30%，但在肿瘤淋巴细胞浸润活跃的病例中，一次性手术切净率更高。
Abstract:
Objective To investigate the clinical and pathological features of melanoma. Methods 10 cases of facial melanoma diagnosed in the Department of Dermatology, the First Affiliated Hospital of Xinjiang Medical University and removed by Slow Mohs micrographic surgery were retrospective ly analyzed and collected clinicopathological data and treatment of the patients. Results Facial melanoma is usually clinically manifested as patches with unclear boundaries, papules and nodules of varying sizes can be seen on them, and some nodules can be ulcerated; in histopathology, they are manifested as epidermal atrophy and epidermal junctions. Or the superficial and middle dermis can be seen in nests or scattered heterosexual black cells, growing along the basal layer, and sunlight elastic fibrosis can be seen in the superficial and middle dermis, with slow Mohs micrography, the negative rate of one-time surgical resection was low, and the tumor could be completely removed only after 2 to 3 times of dilatation. Conclusion The skin lesions of facial melanoma patients were located at the exposure site, with unclear boundaries and obvious skin atrophy. When the surgical expansion range was determined according to the thickness of Breslow, the one-time surgical resection net rate was only 30％, but it was higher in the cases with active tumor lymphocyte infiltration

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更新日期/Last Update: 2022-01-18