[1]岳 敏综述,谭 军审校.平阳霉素对增生性瘢痕的治疗研究进展[J].中国美容医学,2022,(5):172-175.
　YUE Min,TAN Jun.Advances in the Treatment of Hypertrophic Scar with Pingyangmycin[J].Medical Aesthetics and Beauty,2022,(5):172-175.
点击复制

平阳霉素对增生性瘢痕的治疗研究进展()
分享到：

《中国美容医学》[ISSN:1008-6445/CN:61-1347/R]

卷:
期数:
2022年5期
页码:
172-175
栏目:
出版日期:
2022-05-10

文章信息/Info

Title:
Advances in the Treatment of Hypertrophic Scar with Pingyangmycin
文章编号:
1008-6455（2022）05-0172-04
作者:
岳 敏1; 2综述; 谭 军2审校
(1.湖南师范大学附属第一医院&湖南省人民医院 湖南 长沙 410005 ;2.湖南省人民医院整形与激光美容外科 湖南 长沙 410005 )
Author(s):
YUE Min1; 2; TAN Jun2
(1.The First Affiliated Hospital of Hunan Normal University & the Peoples Hospital of Hunan Province,Changsha 410005,Hunan,China; 2.Department of Plastic & Laser Cosmetic Surgery,the Peoples Hospital of Hunan Province,Changsha 410005,Hunan,China)
关键词:
增生性瘢痕; 瘢痕疙瘩; 平阳霉素; 博来霉素; 博来霉素A5
Keywords:
hypertrophic scars;  keloids;  pingyangmycin;  bleomycin;  bleomycin A5
分类号:
R619+.6
文献标志码:
A [
摘要:
增生性瘢痕是皮肤损伤愈合后以组织纤维化、胶原形成与降解平衡失调、胶原过度沉积为特征，是机体皮肤受损达真皮网状层及以下时形成的纤维愈合，属于机体受伤后创面异常修复的结果。近年来，研究发现平阳霉素在增生性瘢痕的治疗中对抑制成纤维细胞的增殖、影响胶原合成和血管生成有重要作用。临床上也发现平阳霉素对增生性瘢痕有较好的疗效。而相对于单独使用平阳霉素来说，与其他方法联合使用来治疗增生性瘢痕更有效果。本文以平阳霉素对增生性瘢痕的治疗作用机制和临床应用进行综述，以期为增生性瘢痕的治疗提供新思路。
Abstract:
Hypertrophic scar is characterized by tissue fibrosis, imbalance of collagen formation and degradation, and excessive collagen deposition after skin injury is healed. It is the fibrous healing formed when the body’s skin is damaged to the dermal reticular layer and below. It is an abnormal wound after the body is injured. The result of the repair. In recent years, studies have found that pingyangmycin plays an important role in inhibiting the proliferation of fibroblasts and affecting collagen synthesis and angiogenesis in the treatment of hypertrophic scars. In the clinic, it has also been found that pingyangmycin has a good effect on hypertrophic scars. Now the author reviews the mechanism and clinical application of pingyangmycin in the treatment of hypertrophic scars, and provides new ideas for the treatment of hypertrophic scars

相似文献/References:

[1]陈 方. 咪喹莫特调节Th1、Th2细胞相关趋化因子对兔耳增生性瘢痕创面愈合和瘢痕增生的影响[J].中国美容医学,2018,(03):100.
　CHEN Fang. Effect of Imiquimod Regulating Th1 and Th2 Cell-associated Chemokines on Wound Healing and Scar Proliferation in Rabbits[J].Medical Aesthetics and Beauty,2018,(5):100.
[2]王春贵,张宝林.手术切除联合放疗与博来霉素注射治疗耳廓瘢痕疙瘩疗效对比[J].中国美容医学,2018,(06):71.
　WANG Chun-gui,ZHANG Bao-lin. Comparison of Curative Effect between Combined Radiotherapy and Bolamycin Injection after Auricle Keloid Resection[J].Medical Aesthetics and Beauty,2018,(5):71.
[3]黄显翔,张 伟,叶光荣,等. CO2点阵激光治疗增生性瘢痕的临床疗效及对TGF-β1表达的影响[J].中国美容医学,2018,(08):108.
　HUANG Xian-xiang,ZHANG Wei,YE Guang-rong,et al.Analysis of the Clinical Effects and Influence on Expression of TGF-β1 of CO2 Lattice Laser in the Treatment of Hypertrophic Scar[J].Medical Aesthetics and Beauty,2018,(5):108.
[4]谢 彬. 深度烧伤患者弹力绷带压力治疗对增生性瘢痕恢复情况的影响[J].中国美容医学,2018,(10):62.
　XIE Bin. Effect of Pressure Treatment with Elastic Bandage on Recovery of Hypertrophic Scar in Patients with Deep Burn[J].Medical Aesthetics and Beauty,2018,(5):62.
[5]徐志山,王洪一,钟黎明,等. 苦参碱对瘢痕疙瘩成纤维细胞生长的抑制作用实验研究[J].中国美容医学,2018,(10):137.
　XU Zhi-shan,WANG Hong-yi,ZHONG Li-ming,et al. Inhibitory Effect of Matrine on the Growth of Keloid Fibroblasts[J].Medical Aesthetics and Beauty,2018,(5):137.
[6]吕春风,刘胜达,种 红,等. 皮瓣移植术后应用高压氧治疗对皮瓣存活的影响研究[J].中国美容医学,2019,(01):31.
　LYU Chun-feng,LIU Sheng-da,CHONG Hong,et al. Effect of Hyperbaric Oxygen Therapy on the Survival of Skin Flap after Flap Transplantation[J].Medical Aesthetics and Beauty,2019,(5):31.
[7]俞 舜. 微等离子体射频联合曲安奈德超声导入治疗增生性瘢痕疗效分析[J].中国美容医学,2019,(02):63.
　YU Shun. Clinical Study on Microplasma Radiofrequency Combined with Ultrasonic ImportingTriamcinolone Acetonide in the Treatment of Hypertrophic Scar[J].Medical Aesthetics and Beauty,2019,(5):63.
[8]王 琳,唐海玲,胡志坤. 硬皮病及瘢痕疙瘩与硬化萎缩性苔藓患者LIGHT及其受体LTβR和HVEM病理生理学差异分析[J].中国美容医学,2019,(02):80.
　WANG Lin,TANG Hai-ling,HU Zhi-kun. Difference Analysis of Pathophysiological Significance between Light and ItsReceptor LTβR and Hvem in Patients with Scleroderma,Keloid and SclerosingAtrophic Moss[J].Medical Aesthetics and Beauty,2019,(5):80.
[9]史 敏,李 娜,郭晓波,等.miR-21调控PTEN/PI3K/Akt通路抑制增生性瘢痕形成的机制研究[J].中国美容医学,2019,(03):92.
　SHI Min,LI Na,GUO Xiao-bo,et al. Mechanism of miR-21 Inhibiting Human Hypertrophic Scar Formation by RegulatingPTEN/PI3K/Akt Pathway[J].Medical Aesthetics and Beauty,2019,(5):92.
[10]史 敏 李 娜 陈 雷 刘兆旺 魏超鹏综述,封兴华审校. 自噬、miRNA与增生性瘢痕的研究进展[J].中国美容医学,2019,(04):160.
　SHI Min,LI Na,CHEN Lei,et al. Advance in Research on Autophagy, miRNA and Hypertrophic Scar[J].Medical Aesthetics and Beauty,2019,(5):160.
[11]李 丽,王 林. 正常皮肤与病理性瘢痕组织中HIF-1α和促炎细胞因子水平比较及两者相关性研究[J].中国美容医学,2019,(04):71.
　LI Li,WANG Lin. Levels of HIF-1α and Proinflammatory Cytokines in Normal Skin and PathologicalScar Tissue and Their Correlation[J].Medical Aesthetics and Beauty,2019,(5):71.
[12]毛姝然 综述,肖志波 审校.病理性瘢痕的治疗现状及研究进展[J].中国美容医学,2022,(1):181.
　MAO Shuran,XIAO Zhibo.Treatment Status and Research Progress of Pathologic Scars[J].Medical Aesthetics and Beauty,2022,(5):181.
[13]李仕一 综述,陈敏亮 审校.病理性瘢痕的发生机制及治疗新进展[J].中国美容医学,2022,(4):169.
　LI Shiyi,CHEN Minliang.Research Hotspots in Pathogenesis and Prevention of Pathological Scars[J].Medical Aesthetics and Beauty,2022,(5):169.
[14]杨 帆 综述,李跃军 审校.注射A型肉毒毒素在病理性瘢痕防治中的应用进展[J].中国美容医学,2022,(8):197.
　YANG Fan,LI Yuejun.Advances in the Research of Prevention and Treatment of Pathological Scars by Injecting Botulinum Toxin Type A[J].Medical Aesthetics and Beauty,2022,(5):197.
[15]李程丽,欧阳华伟.曲安奈德局部注射治疗儿童病理性瘢痕的单组率Meta分析[J].中国美容医学,2023,(1):102.
　LI Chengli,OUYANG Huawei.A Single-group Rate Meta-analysis of Local Injection of Triamcinolone Acetonide in the Treatment of Children with Pathological Scars[J].Medical Aesthetics and Beauty,2023,(5):102.
[16]贾文斌 综述,谭 谦 审校.病理性瘢痕的非手术治疗新进展[J].中国美容医学,2023,(1):183.
　JIA Wenbin,TAN Qian.New Progress in Non-surgical Treatment of Pathological Scar[J].Medical Aesthetics and Beauty,2023,(5):183.
[17]潘 铃 综述,李冬青 吴信峰 审校.长链非编码RNA在皮肤纤维化疾病中的研究进展[J].中国美容医学,2023,(2):186.
　PAN Ling,LI Dongqing,WU Xinfeng.The Research Progress of Long non-coding RNA in Skin Fibrotic Diseases[J].Medical Aesthetics and Beauty,2023,(5):186.
[18]刘建科 杨喜明 综述,高栋梁 审校.非编码RNA对瘢痕疙瘩形成的影响机制研究进展[J].中国美容医学,2023,(11):199.[doi:10.15909/j.cnki.cn61-1347/r.006012]
　LIU Jianke,YANG Ximing,GAO Dongliang.Research Progress on the Mechanism of Infl uence of Non-coding RNA on Keloid Formation[J].Medical Aesthetics and Beauty,2023,(5):199.[doi:10.15909/j.cnki.cn61-1347/r.006012]
[19]胡智瀚 王铄链 崔振芸 综述,刘 毅 审校.病理性瘢痕的注射治疗进展[J].中国美容医学,2024,(1):191.
　HU Zhihan,WANG Shuolian,CUI Zhenyun,et al.Progress in the Treatment of Pathological Scars by Injection Therapy[J].Medical Aesthetics and Beauty,2024,(5):191.

更新日期/Last Update: 2022-06-02